HarmonyCa is comprised of Calcium Hydroxyapatite microspheres that are strongly embedded within cross-linked Hyaluronic acid. Calcium Hydroxyapatite stimulates collagen production, while Hyaluronic acid forms a supporting extracellular matrix, which modulates fibroblast proliferation.

The microsphere diameter (25-45 microns) minimizes the risk of particle migration and phagocytosis which, in addition to the microspheres’ integration within a net of cross-linked Hyaluronic acid, ensures a smooth appearance with deep hydration of the skin. HarmonyCa contains lidocaine and should be injected in the deep- and sub-dermal layers.